In this free webinar, you will learn about:
- Sequential Trial Design
What options are available to you
- Interim Monitoring & Sample Size Re-estimation
The Cui, Hung & Wang method
The Chen, DeMets & Lan method
- Practical Implementation of Sequential Design
How to correctly design a Group Sequential Design
How to make interim adaptations to your Sequential Design
More about the webinar
Sequential designs are a very powerful and useful class of adaptive trials that have become common in the clinical trial landscape.
Due to the complex nature of these types of designs, some unique challenges are often encountered with their implementation. In addition, these types of designs often attract greater regulatory scrutiny.
While Group Sequential Designs which employ an error spending approach are the most common type of sequential design, other options are also available.
In this webinar, we will explore the broad area of sequential designs and interim monitoring of these trials.
In addition, we will examine the issues encountered in the implementation of these designs through the use of a detailed worked example, illustrating some of the tools available in nQuery.
